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IMERGARD WP

IMERGARD WP Vector control for disease mitigation

A new mode of action IRS with at least 11 months' residual efficacy.

  • Physical mode of action
  • Long-term residual control
  • Manages insecticide resistance
  • 100% natural, safe and effective

Imergard WP IRS Awareness Training, Umme Tanzania, 18 September 2018

Imergard™ WP (wettable powder) mechanical insecticide is a perlite-based indoor and outdoor residual spray designed to provide a physical mode of action against mosquito vectors.

According to data provided in the 2019 World Malaria Report released by the World Health Organization, there were an estimated 405,000 deaths from malaria globally in 2018. Children under the age of 5 years accounted for 67% (272,000) of all malaria deaths worldwide.

Indoor residual sprays (IRS) have been an effective strategy to control malaria transmission, and have helped reduce the number of deaths in recent years. However, mosquitoes evolve to become resistant to these treatments.

 

A new mode of action IRS

Imergard WP (Wettable Powder) is a mechanical insecticide providing a physical mode of action. It is applied to interior walls using standard backpack spray equipment. When the mosquito lands on a treated surface, there is a static transfer of Imergard WP particles, which absorb the lipid layer necessary for the mosquito’s survival.

Tried and tested during an 8-month study in Tanzania

In a 2019 community trial in Tanzania, where over 4,000 houses were treated, Imergard WP was able to control the malaria parasite as effectively as the gold standard Positive Control , a micro-encapsulated Pirimiphos-methyl IRS. At the conclusion of the eight-month study, Imergard WP maintained 100% efficacy after 72 hours against a threshold target of 80% mortality. Imergard WP held its own against the gold standard which is an impressive result for a mechanical insecticide, considering that the mosquitos in this study were susceptible to micro-encapsulated Pirimiphos-methyl.

Figure 1.

72 Hour Residual Efficacy of Imergard WP and the gold standard by month after spraying up to 8 months against Anopheles gambiae s.s. Ifakara Strain

Figure 2.

24 & 72 Hour Residual Efficacy of Imergard WP and gold standard by month after spraying 6 to 8 months against against pyrethroid resistant Anopheles arabiensis Kining’ina strain

High user acceptance

The primary objective of employing IRS as a strategy for malaria control is to limit the spread of the malaria parasite. After a blood meal, mosquitoes typically rest indoors prior to ovipositioning. If mosquitoes don’t live longer than 10-14 days they will not live long enough to transmit the malaria parasite.

The advantage of Imergard™ WP is that it provides a physical mode of action. It will deter cross-chemical resistance development and complement existing IRS chemistry.

 

Imergard WP limits the spread of the malaria-carrying parasite

The primary objective of employing IRS as a strategy for malaria control is to limit the spread of the malaria parasite. After a blood meal, mosquitoes typically rest indoors prior to ovipositioning. If mosquitoes don’t live longer than 10-14 days they will not live long enough to transmit the malaria parasite.

The advantage of Imergard™ WP is that it provides a physical mode of action. It will deter cross-chemical resistance development and complement existing IRS chemistry.

 

No physical, chemical, human health or environmental hazards

The active ingredient of Imergard WP is perlite which has been processed to release its insecticidal properties. Imergard WP has demonstrated efficacy against multiple Anopheles, Aedes and Culex s.s. It has a Toxicity Class IV rating which is the lowest rating and is non-toxic to bees.

Imergard WP - Features & benefits:

  • Pending WHO Prequalification, WHO PQ, with a commercial launch anticipated in 2021
  • Pending US Environmental Protection Agency approval as a biopesticide for targeted applications
  • A physical mode of action offers a new resistance management tool to deter cross-chemical resistance development
  • A 5-year shelf life so it can be distributed to application sites months or years in advance
  • No odor and residents can enter the house immediately after application
  • Visual application cues allow sprayers and home residents to see where it has been sprayed
  • Applied with standard IRS backpack sprayers
  • Produced from a sustainable resource
  • Does not heat degrade so can be applied to tin ceilings
  • Demonstrated efficacy against multiple Anopheles, Aedes and Culex mosquitoes
  • Lowest Toxicity Class IV rating and is non-toxic to bees

 

Vector Control Using Imergard™WP (Spanish)

Vector Control Using Imergard™WP (Swahili)

We offer a full range of custom formulation and technical and process support services to help you match the right mineral grade to your application requirement.

Please contact us, we will be only too happy to help

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